DEGISCO has released a new edition of the Desktop Grids for eScience Road Map on July 11, 2011. The document is comprised of two parts. The first part constitutes a bird view of all the relevant topics to be considered when setting up a Desktop Grid infrastructure. This management part is addressed to political stakeholders and the general public. The second part offers a detailed and step-by-step description in five chapters of all the challenges and issues to be solved including relevant links to background information and practical examples. This technical part is aimed at Desktop Grid operators, scientific users, the academic user community, legal experts, and volunteer computing organisations. The Road map documents are available in the IDGF download section.